Structure of PDB 5f5f Chain G Binding Site BS02

Receptor Information
>5f5f Chain G (length=148) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLSSNLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVV
QRLEPRFPQASKTSIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRTYE
ALRREHDSQIVQIAMEAGLRIAPDQWSSLLYGDQSHKSHMQSIIDKLQ
Ligand information
>5f5f Chain D (length=20) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugacugcguuuuaggaguua
.<<<<.<......>.>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5f5f Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		A299 P300 D301 K314
Binding residue
(residue number reindexed from 1)		A122 P123 D124 K137
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:5f5f, PDBe:5f5f, PDBj:5f5f
PDBsum5f5f
PubMed27010430
UniProtQ4VGL6|RC3H1_MOUSE Roquin-1 (Gene Name=Rc3h1)

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