Structure of PDB 5eea Chain G Binding Site BS02

Receptor Information
>5eea Chain G (length=63) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQN
RRVKEKKVLAKVK
Ligand information
Receptor-Ligand Complex Structure
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PDB5eea Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.
Resolution2.195 Å
Binding residue
(original residue number in PDB)		R220 P222 K243 R246 Q265 R268
Binding residue
(residue number reindexed from 1)		R4 P6 K27 R30 Q49 R52
Binding affinityPDBbind-CN: Kd=41nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5eea, PDBe:5eea, PDBj:5eea
PDBsum5eea
PubMed29638214
UniProtQ92826|HXB13_HUMAN Homeobox protein Hox-B13 (Gene Name=HOXB13)

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