Structure of PDB 5bsg Chain G Binding Site BS02

Receptor Information
>5bsg Chain G (length=269) Species: 3880 (Medicago truncatula) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IPADSYTLGFIGAGKMAESIAKGAVRSGVLSPSRIKTAIHSNPARRTAFE
SIGITVLSSNDDVVRDSNVVVFSVKPQLLKDVVLKLKPLLTKDKLLVSVA
AGIKMKDLQEWAGHERFIRVMPNTAATVGEAASVMSLGGAATEEDANLIS
QLFGSIGKIWKADDKYFDAITGLSGSGPAYIYLAIEALADGGVAAGLPRD
LALSLASQTVLGAASMATQSGKHPGQLKDDVTSPGGTTIAGVHELEKAGF
RGILMNAVVAAAKRSQELS
Ligand information
Ligand IDCL
InChIInChI=1S/ClH/h1H/p-1
InChIKeyVEXZGXHMUGYJMC-UHFFFAOYSA-M
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cl-]
FormulaCl
NameCHLORIDE ION
ChEMBL
DrugBankDB14547
ZINC
PDB chain5bsg Chain G Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5bsg The structure of Medicago truncatula delta (1)-pyrroline-5-carboxylate reductase provides new insights into regulation of proline biosynthesis in plants.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		S238 T243
Binding residue
(residue number reindexed from 1)		S233 T238
Annotation score1
Enzymatic activity
Enzyme Commision number 1.5.1.2: pyrroline-5-carboxylate reductase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004735 pyrroline-5-carboxylate reductase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006561 proline biosynthetic process
GO:0055129 L-proline biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5bsg, PDBe:5bsg, PDBj:5bsg
PDBsum5bsg
PubMed26579138
UniProtG7KRM5

[Back to BioLiP]