Structure of PDB 4qqx Chain G Binding Site BS02

Receptor Information
>4qqx Chain G (length=887) Species: 269800 (Thermobifida fusca YX) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPLDLRFWAKERGLRGKTYPLVCHSLDAAAAALVLWNEYLSPGLRDTIAS
SMETDEEHAGHCIAFWAGLHDIGKLTREFQQQIAIDLSAYPGEELSGEQR
SHAAATGKWLPFALPSLGYPNGGLVTGLVAQMLGGHHGTFHPHPSFQSRN
PLAEFGFSSPHWEKQRHALLHAVFDATGRPTPPDMLDGPTASVVCGLVIL
ADWLVSQEDFLLERLTSLPADGSASALRAHFETSLRRIPSLLDAAGLRPI
TVPPATFTESFPHLSKPNGLQASLAKHLPCLCTGPGLVLITAPMGEGKTE
AAYHVADLLGKATGRPGRFLALPTMATADQMHTRLKEYARYRVESSTLAL
LHSMAWLNPDYAPADPFAATDWLMGRKRGLLAPWAVGTIDQALMAVLRAK
HNALRLFGLAGKVVVVDEAHAVDPYMQVLLEQLLRWLGTLDVPVVLLSAT
LHHSIANSLVKAYLEGARGRRWNRSEPQPVSEVSYPGWLHVDARIGKVTR
SSDVDPLPIATTPRKPLEVRLVDVPVKEGALNRSTVLAKELTPLVKQAAI
ICTTVAEAQGVYDLLSQWFATLPDLYLLHSRFPNRQRTEITATIVDLFGK
EGAQSGRRPTVLVATQVVEQSLDLDVDLMISDLAPVSLLLQRAGRCWRHE
HLGIINRPQWAKQPELVVLTPEQNRAPWFPRSWTSVYPLALLQRTYTLLR
RRNGAPVQIPEDVQQLVDDVYDDDSLAEDLEADMERMGEELAQRGLARNA
VIPDPDDAEDNLNGLTEFSVLATRFGAGSVRVLCYYVGNRWLDPECTVEF
PEQGTGREGRFTMADCRDLVARTIPVRMGPWASQLTEDNHPPEAWRESFY
LRDLVLIPQRVTDEGAVLPTETGGREWLLDPCKGLIF
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain4qqx Chain G Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4qqx Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Resolution3.34 Å
Binding residue
(original residue number in PDB)		D84 K87 H115 H149 H150
Binding residue
(residue number reindexed from 1)		D71 K74 H102 H136 H137
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0051607 defense response to virus
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4qqx, PDBe:4qqx, PDBj:4qqx
PDBsum4qqx
PubMed25132177
UniProtQ47PJ0

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