Structure of PDB 4h4l Chain G Binding Site BS02

Receptor Information
>4h4l Chain G (length=142) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLHKERRIGRLSVLLLLNEQVEELERDGWKVCLGKVGSMDAHKVIAAIET
ASKKSGVIQSEGYRESHALYHATMEALHGVTRGEMLLGSLLRTVGLRFAV
LRGNPYESEAEGDWIAVSLYGTIGAPIKGLEHETFGVGINHI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4h4l Chain G Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4h4l Alternative binding modes of l-histidine guided by metal ions for the activation of the antiterminator protein HutP of Bacillus subtilis.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H73 H77
Binding residue
(residue number reindexed from 1)		H67 H71
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
Biological Process
GO:0006547 L-histidine metabolic process
GO:0010628 positive regulation of gene expression

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Molecular Function
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Biological Process
External links
PDB RCSB:4h4l, PDBe:4h4l, PDBj:4h4l
PDBsum4h4l
PubMed23748184
UniProtP10943|HUTP_BACSU Hut operon positive regulatory protein (Gene Name=hutP)

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