Structure of PDB 3u9m Chain G Binding Site BS02

Receptor Information
>3u9m Chain G (length=157) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFKE
FKMHEQIENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEY
EQLNYAKQLKERLEAFTRDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKK
VIAQHCS
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain3u9m Chain G Residue 208 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3u9m The Structural Basis of Iron Sensing by the Human F-box Protein FBXL5.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		H15 H57 E61 E130
Binding residue
(residue number reindexed from 1)		H12 H54 E58 E127
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006879 intracellular iron ion homeostasis

View graph for
Biological Process
External links
PDB RCSB:3u9m, PDBe:3u9m, PDBj:3u9m
PDBsum3u9m
PubMed22492618
UniProtQ9UKA1|FBXL5_HUMAN F-box/LRR-repeat protein 5 (Gene Name=FBXL5)

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