Structure of PDB 3q5e Chain G Binding Site BS02

Receptor Information
>3q5e Chain G (length=384) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKG
KSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRTGIQIWSEIFLINKPD
GKKVAVLLMDTQGTRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLF
TEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVR
KHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWL
LSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEA
NNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRG
VKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3q5e Chain G Residue 448 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3q5e Structural basis for the nucleotide-dependent dimerization of the large G protein atlastin-1/SPG3A.
Resolution3.013 Å
Binding residue
(original residue number in PDB)		D146 Q148
Binding residue
(residue number reindexed from 1)		D110 Q112
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.-
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:3q5e, PDBe:3q5e, PDBj:3q5e
PDBsum3q5e
PubMed21220294
UniProtQ8WXF7|ATLA1_HUMAN Atlastin-1 (Gene Name=ATL1)

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