Structure of PDB 3izz Chain G Binding Site BS02

Receptor Information

>3izz Chain G (length=121) Species: 562 (Escherichia coli)

IQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGK
VKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFG
PVTRELRSEKFMKIISLAPEV

Ligand information

>3izz Chain B (length=118)

ggccguaacuauaacggucucggguaaguuccgacugauaccgcccaaga
guucauaucgacggcgguguuuggauggcuguucgccaucugcuccuagu
acgagaggaccggagugg

.<<<<<.......>>>>>.<<<<.......>>>><<...<<<<<<...<<
.......>>...>>>>>>....>><<<<<.....>>>>><<<<<<<....
...........>>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3izz Insertion domain within mammalian mitochondrial translation initiation factor 2 serves the role of eubacterial initiation factor 1.
• Resolution: 10.8 Å
• Binding residue (original residue number in PDB): I22 H29 R30 T42 K44 V57
• Binding residue (residue number reindexed from 1): I21 H28 R29 T41 K43 V56

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding
• GO:0070180 large ribosomal subunit rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:3izz, PDBe:3izz, PDBj:3izz
• PDBsum: 3izz
• PubMed: 21368145
• UniProt: P0ADY3|RL14_ECOLI Large ribosomal subunit protein uL14 (Gene Name=rplN)