Structure of PDB 1gxc Chain G Binding Site BS02
Receptor Information
>1gxc Chain G (length=116) Species:
9606
(Homo sapiens) [
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PWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSK
KHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIAL
SLSRNKVFVFFDLTVD
Ligand information
>1gxc Chain K (length=8) Species:
32630
(synthetic construct) [
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HFDTYLIR
Receptor-Ligand Complex Structure
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PDB
1gxc
Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
N186 E188 V200
Binding residue
(residue number reindexed from 1)
N95 E97 V109
Enzymatic activity
Enzyme Commision number
2.7.11.1
: non-specific serine/threonine protein kinase.
External links
PDB
RCSB:1gxc
,
PDBe:1gxc
,
PDBj:1gxc
PDBsum
1gxc
PubMed
12049740
UniProt
O96017
|CHK2_HUMAN Serine/threonine-protein kinase Chk2 (Gene Name=CHEK2)
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