Structure of PDB 8gzu Chain FS Binding Site BS02

Receptor Information

>8gzu Chain FS (length=188) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MSAILKRAAKYKRVSSILCEGEAHLRDPFTPPPVILKPPAPRKDKKPDDI
TDFPAQKLIPLPESIPYQEGKYRPASIPMVAGFFPYNCYLQQGKVYSWCS
CGISQSGPWCDGLCNSVVTRCRPVVFNVSQSGYYKICNCKFSANAPFCNN
THRKMVRYHHQTHRGFYEIWGAALFVLGWVYMGFNYYT

Ligand information

InChI=1S/2Fe.2S

NIXDOXVAJZFRNF-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04	[Fe]1S[Fe]S1
CACTVS 3.341 OpenEye OEToolkits 1.5.0	S1[Fe]S[Fe]1

Formula

Fe2 S2

Name

FE2/S2 (INORGANIC) CLUSTER

ChEMBL

DrugBank

ZINC

PDB chain

8gzu Chain FS Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8gzu Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Resolution	4.18 Å
Binding residue (original residue number in PDB)	P85 C137 N138 C139 C148 N149 N150 T151 H152
Binding residue (residue number reindexed from 1)	P85 C137 N138 C139 C148 N149 N150 T151 H152
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0046872	metal ion binding
GO:0051537	2 iron, 2 sulfur cluster binding

	Biological Process
GO:0106034	protein maturation by [2Fe-2S] cluster transfer

	Cellular Component
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0016020	membrane
GO:0043231	intracellular membrane-bounded organelle

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Cellular Component

External links

PDB	RCSB:8gzu, PDBe:8gzu, PDBj:8gzu
PDBsum	8gzu
PubMed	37248254
UniProt	I7M8P0

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