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Receptor Information

>6sgb Chain FF (length=408) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MKRIVVPHRWSEMNRVEHPPLMMKQLFQGVCGGLRWLETKSLAQYLAVRA
IEEGYPSTPGVRSLQVTKQKRLVSYDVLDCTLGSGYHAGAVLENGGPYTR
VVALDCDHDAMHAARDLVEEFGGDRFRFYCCKMSEAKAMFGERSFDAIMI
DGGVSDTQLEDPERGFLLDDEGGHRLDMRFGPQMGVGALEYLNTVSQHTL
VSSLLAYGLLEYGQAMKMSRAITRRKPFVDSREVLTCIEQAGDELPEGGW
RSQGSRRKSPMSWKFLTSLRCIINNEMYELRQGIENALLMLRDDGRLVVF
SRLPWEERLVRGTVDDHPHALLSYVEDISIDDVQIYGFTRHAKMWVITRA
ASSAYALKNTTTLTEEKFRESSVRWLTGMYAGQTHGFPANNFTFENFERK
EWVTLRRN

>6sgb Chain CA (length=609) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

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Receptor-Ligand Complex Structure

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Structure summary

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PDB	6sgb Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Resolution	3.3 Å
Binding residue (original residue number in PDB)	E264 R273 Q293 Y433 A434 G435 Q436 T437 H438 T446 F447 N449 E451 R452
Binding residue (residue number reindexed from 1)	E211 R220 Q240 Y380 A381 G382 Q383 T384 H385 T393 F394 N396 E398 R399

Enzyme Commision number

2.1.1.-

	Molecular Function
GO:0008168	methyltransferase activity
GO:0071424	rRNA (cytosine-N4-)-methyltransferase activity

	Biological Process
GO:0032259	methylation
GO:0070475	rRNA base methylation

	Cellular Component
GO:0005739	mitochondrion

PDB	RCSB:6sgb, PDBe:6sgb, PDBj:6sgb
PDBsum	6sgb
PubMed	31515389
UniProt	Q57W60

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Structure of PDB 6sgb Chain FF Binding Site BS02