Structure of PDB 8sp1 Chain F Binding Site BS02

Receptor Information
>8sp1 Chain F (length=92) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKG
NRKKMTYQKMARALRNYGKTGIIHKTAKKKLTYQFSGEVLGR
Ligand information
Receptor-Ligand Complex Structure
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PDB8sp1 Dissecting the hydration and dynamics of protein/DNA readout: Modeling with the ETS-family transcription factor PU.1
Resolution1.62 Å
Binding residue
(original residue number in PDB)		R171 W213 K217 K221 M223 Q226 K227 Y235
Binding residue
(residue number reindexed from 1)		R3 W45 K49 K53 M55 Q58 K59 Y67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:8sp1, PDBe:8sp1, PDBj:8sp1
PDBsum8sp1
PubMed38042148
UniProtP17433|SPI1_MOUSE Transcription factor PU.1 (Gene Name=Spi1)

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