Structure of PDB 8jr0 Chain F Binding Site BS02

Receptor Information
>8jr0 Chain F (length=469) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTSGRVVRVTGPVVDVEFPRGSIPELFNALHAEITFESLAKTLTLEVAQH
LGDNLVRTISLQPTDGLVRGVEVIDTGRSISVPVGEGVKGHVFNALGDCL
DEPGYGEKFEHWSIHRKPPAFEELEPRTEMLETGLKVVDLLTPYVRGGKI
ALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELAE
ANVLKDTALVFGQMDEPPGTRMRVALSALTMAEWFRDEQGQDVLLFIDNI
FRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQ
AVYVPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTIL
DPSVVGDEHYRVAQEVIRILQRYKDLQDIIAILGIDELSEEDKQLVNRAR
RIERFLSQNMMAAEQFTGQPGSTVPVKETIEAFDRLCKGDFDHVPEQAFF
LIGGLDDLAKKAESLGAKL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8jr0 Chain F Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8jr0 Structure of Mycobacterium tuberculosis ATP synthase
Resolution2.8 Å
Binding residue
(original residue number in PDB)		T178 E203
Binding residue
(residue number reindexed from 1)		T161 E186
Annotation score1
Enzymatic activity
Enzyme Commision number 7.1.2.2: H(+)-transporting two-sector ATPase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall
GO:0045259 proton-transporting ATP synthase complex
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jr0, PDBe:8jr0, PDBj:8jr0
PDBsum8jr0
PubMed38961288
UniProtP9WPU5|ATPB_MYCTU ATP synthase subunit beta (Gene Name=atpD)

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