Structure of PDB 8it0 Chain F Binding Site BS02

Receptor Information
>8it0 Chain F (length=450) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRNKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLDKGVDFWSTIE
KEIRENTCKFLIVSSTAGNKREGVLKELAVATKVKKHLQDDMFIIPLAID
ENLSYDDINIEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKS
NLLYQQIFLHDKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDV
RTLAFPAIRYKEYLCTFAWEYDFIHQLPKTETYNGQESIRISTSDILSGR
YDTDFIRNYECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKL
EKDKFEKIKLVGKQKNKYWHFGISAAGKLYPSPVLMVSSHIIFTMDGINL
IKSKSIQHSSRRKQGKNWWNDKWREKLLAFIRFLSDDQNAIYLNVGSEEK
ILISNKPLKFFGKMSYVTPSEVTLEEESVLADINNFEEDTEDLDELEDIE
Ligand information
>8it0 Chain G (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugagguaguagguuguauagu
.....................
Receptor-Ligand Complex Structure
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PDB8it0 Nucleic acid-triggered NADase activation of a short prokaryotic Argonaute.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		K196 K211 K289 H340 R361 R362 N434 E437 E438
Binding residue
(residue number reindexed from 1)		K196 K211 K289 H340 R361 R362 N434 E437 E438
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007165 signal transduction

View graph for
Biological Process
External links
PDB RCSB:8it0, PDBe:8it0, PDBj:8it0
PDBsum8it0
PubMed37783228
UniProtA0A1I7NFG5

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