Structure of PDB 8eak Chain F Binding Site BS02

Receptor Information
>8eak Chain F (length=491) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFE
WPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEV
PSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFD
IYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEAL
ALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYT
TGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDED
RVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDN
INLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTL
RKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLE
ALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8eak Chain F Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8eak Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Resolution2.67 Å
Binding residue
(original residue number in PDB)		H144 C149 C171 C174
Binding residue
(residue number reindexed from 1)		H40 C45 C67 C70
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0032508 DNA duplex unwinding

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Molecular Function
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Biological Process
External links
PDB RCSB:8eak, PDBe:8eak, PDBj:8eak
PDBsum8eak
PubMed36499022
UniProtQ9UXG1|MCM_SACS2 Minichromosome maintenance protein MCM (Gene Name=MCM)

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