Structure of PDB 8c8x Chain F Binding Site BS02

Receptor Information
>8c8x Chain F (length=177) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLD
NAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFE
RLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRG
LDITITTTAKSDEEGRALLAAFDFPFR
Ligand information
>8c8x Chain B (length=119) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugccuggcggccguagcgcgguggucccaccugaccccaugccgaacuca
gaagugaaacgccguagcgccgaugguaguguggggucuccccaugcgag
aguagggaacugccaggca
<<<<<<<<<<.....<<<<<<<<....<<<<<<<.............>>>
>..>>>...>>>>>>.>>.<<...<...<<<<<<<<...>>>>>>>>...
..>.>>...>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB8c8x Cryo-EM captures early ribosome assembly in action.
Resolution3.93 Å
Binding residue
(original residue number in PDB)		M25 Q26 R29 Q62 K63 L65 K68 R91 R94
Binding residue
(residue number reindexed from 1)		M25 Q26 R29 Q62 K63 L65 K68 R91 R94
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8c8x, PDBe:8c8x, PDBj:8c8x
PDBsum8c8x
PubMed36797249
UniProtP62399|RL5_ECOLI Large ribosomal subunit protein uL5 (Gene Name=rplE)

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