Structure of PDB 8a98 Chain F Binding Site BS02

Receptor Information
>8a98 Chain F (length=142) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSRKSPEYTTLRKSCAPGAIAIILAGRFRGRRAVILKQLPHNGPLVVSGP
MKYNGVPIRRIDSRYVIATSTTVDISSVDTAPITAEVFQRTLVSDARAQL
QKKIDAALIAAIKKDAQGKEKAGYLRSVFTVKPGDAPHRWNW
Ligand information
>8a98 Chain 6 (length=71) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucgaaucgccaccuacaagacuggagcuugcucccucgaaggcgccaag
uauauucaugaucacaagaca
......<.<<<............<<<<....>>>>......>>>......
..................>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8a98 CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT
Resolution2.46 Å
Binding residue
(original residue number in PDB)
A43 G44 R45 R47 P62 M69 K70 G73 P75 R77 R78 Y83 F106 L145 V146 S147 Q154 R179 S180 V181 K185 P186
Binding residue
(residue number reindexed from 1)
A25 G26 R27 R29 P44 M51 K52 G55 P57 R59 R60 Y65 F88 L92 V93 S94 Q101 R126 S127 V128 K132 P133
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8a98, PDBe:8a98, PDBj:8a98
PDBsum8a98
PubMed38722744
UniProtQ4Q4D3

[Back to BioLiP]