Structure of PDB 7x5g Chain F Binding Site BS02

Receptor Information
>7x5g Chain F (length=104) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRDELRAKALHIPFPVEKIINLPVVDFNEMMSKEQFNEAQLALIRDIRRR
GKNKVYAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGENDKSLHLLK
KQLS
Ligand information
Receptor-Ligand Complex Structure
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PDB7x5g Structural basis of transcription regulation by CNC family transcription factor, Nrf2.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		V478 N507 Y510 C514 K518
Binding residue
(residue number reindexed from 1)		V24 N53 Y56 C60 K64
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:7x5g, PDBe:7x5g, PDBj:7x5g
PDBsum7x5g
PubMed36454022
UniProtQ16236|NF2L2_HUMAN Nuclear factor erythroid 2-related factor 2 (Gene Name=NFE2L2)

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