Structure of PDB 7vwz Chain F Binding Site BS02

Receptor Information
>7vwz Chain F (length=478) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAIT
YLLEQYDRVEAEEARLSDLITGFVDPNAENSIDPELAREKFAELRAQYVV
TRDTIKAKGRSHATAQEEILKLSEVFKQFRLKQFDYLVNSMRVMMDRVRT
QERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHD
VSEEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEA
NLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYAT
WWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGRPEELAE
RMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDSA
TTESLRAATHDVLAGLTAREAKVLRMRFGIDMNTDYTLEEVGKQFDVTRE
RIRQIEAKALRKLRHPSRSEVLRSFLDD
Ligand information
>7vwz Chain 2 (length=64) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tgcatccgtgagtcgagggtaataagttgcgagtgaaggttttgttttga
cattcagtgctgtc
Receptor-Ligand Complex Structure
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PDB7vwz Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		R93 Y394 N396 R397 R436 R465 I511 D513 T572 L573 E574
Binding residue
(residue number reindexed from 1)		R1 Y262 N264 R265 R304 R333 I376 D378 T437 L438 E439
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0016987 sigma factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0009408 response to heat
GO:0010468 regulation of gene expression
GO:0045892 negative regulation of DNA-templated transcription
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0000345 cytosolic DNA-directed RNA polymerase complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1903865 sigma factor antagonist complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7vwz, PDBe:7vwz, PDBj:7vwz
PDBsum7vwz
PubMed35641097
UniProtP00579|RPOD_ECOLI RNA polymerase sigma factor RpoD (Gene Name=rpoD)

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