Structure of PDB 7vw7 Chain F Binding Site BS02

Receptor Information

>7vw7 Chain F (length=453) Species: 1354 (Enterococcus hirae)

MIKEYRTIKEVVGPLMAVEKVSGVKYEELIEVRMQNGEIRRGQVLEVQED
KAMVQIFEGTSGINLKNSSVRFLGHPLQLGVSEDMIGRVFDGLGRPKDNG
PEILPEKYLDINGEVINPIARDYPDEFIQTGISAIDHLNTLVRGQKLPVF
SGSGLPHKELAAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQ
TGAIDRSVMFMNLANDPAIERIATPRMALTAAEYLAYEKGMHVLVIMTDM
TNYAEALREISAARREVPGRRGYPGYLYTNLATLFERAGRIRGLKGSVTQ
IPILTMPEDDKTHPIPDLTGYITEGQIILTRELYKSGIQPPIDVLPSLSR
LKDKGTGAGKTREDHAATMNQLFAAYAQGKQAKELAVVLGESALSDIDKI
YAKFAERFENEYVNQGFYTNRTITETLDLGWELLAMLPRTELKRIKDDLL
DKY

Ligand information

• Ligand ID: ALF
• InChI: InChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4
• InChIKey: UYOMQIYKOOHAMK-UHFFFAOYSA-J
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: F[Al-](F)(F)F
• Formula: Al F4
• Name: TETRAFLUOROALUMINATE ION
• DrugBank: DB04444
• PDB chain: 7vw7 Chain C Residue 603

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7vw7 Revealing a Hidden Intermediate of Rotatory Catalysis with X-ray Crystallography and Molecular Simulations.
• Resolution: 3.818 Å
• Binding residue (original residue number in PDB): Y321 R350
• Binding residue (residue number reindexed from 1): Y321 R350
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0005524 ATP binding
• GO:0016787 hydrolase activity
• GO:0046933 proton-transporting ATP synthase activity, rotational mechanism

Biological Process

• GO:0006754 ATP biosynthetic process
• GO:0042777 proton motive force-driven plasma membrane ATP synthesis
• GO:0046034 ATP metabolic process
• GO:1902600 proton transmembrane transport

External links

• PDB: RCSB:7vw7, PDBe:7vw7, PDBj:7vw7
• PDBsum: 7vw7
• PubMed: 35912346
• UniProt: A0A1V8XC32