Structure of PDB 7vpd Chain F Binding Site BS02

Receptor Information
>7vpd Chain F (length=301) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATADPVKDYLKQIGKVPLLNAEQEVELAKRIEAGLFAEDKLANSDKLAPK
LKRELEIIAEDGRRAKNHLLEANLRLVVSLAKRYTGRGMLFLDLIQEGNL
GLIRAVEKFDYTKGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVI
NKLARVQRQMLQDLGREPTPEELAKELDMTPEKVIEVQKYGREPISLHTP
LGEDGDSEFGDLIEDSEAVVPADAVSFTLLQEQLHSVLDTLSEREAGVVS
MRFGLTDGQPKTLDEIGKVYGVTRERIRQIESKTMSKLRHPSRSQVLRDY
L
Ligand information
>7vpd Chain P (length=84) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcgacccggcgcccgctacggagtcaactacgggtagggggtatcgggc
aacgcggcactgaacaccgttgtcatgtgccttg
Receptor-Ligand Complex Structure
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PDB7vpd Structural basis of Streptomyces transcription activation by zinc uptake regulator.
Resolution3.77 Å
Binding residue
(original residue number in PDB)
R292 R296 R364 R367 G411 E412 D413 L472 D473 R483 E484 R487
Binding residue
(residue number reindexed from 1)
R83 R87 R155 R158 G202 E203 D204 L263 D264 R274 E275 R278
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:7vpd, PDBe:7vpd, PDBj:7vpd
PDBsum7vpd
PubMed35871291
UniProtA0A7U9DYK1

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