Structure of PDB 7uvz Chain F Binding Site BS02
Receptor Information
>7uvz Chain F (length=174) Species:
480119
(Acinetobacter baumannii AB0057) [
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LKARYNDELKAKLQEELSIKNVMEIPRITKITLNMGVGAAATDKKLLDGA
VADMQLIAGQKPVVTLARKSIAGFKIRDGWPIGCKVTLRGDQMYEFLDRL
ISIAIPRIRDFRGFSAKSFDGRGNYSMGLKEQIVFPEIDFDKIDRIRGMD
ITITTTARTDDEGRALMRAFGFPF
Ligand information
>7uvz Chain B (length=115) [
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gcuggcgaccauagcaagagugaaccaccugaucccuucccgaacucaga
agugaaaccucuuagcgcugaugguagugugggauuacccaugugagagu
aagucaucgccagcu
<<<<<<<<.....<<<<<<<.....<<<<<<...............>>>.
.>>>....>>>>>.>><<<.......<<<<<<<....>>>>>>>......
.>>>..>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB
7uvz
Streptothricin F is a bactericidal antibiotic effective against highly drug-resistant gram-negative bacteria that interacts with the 30S subunit of the 70S ribosome.
Resolution
2.21 Å
Binding residue
(original residue number in PDB)
N24 M26 E27 Q63 K64 V66 V67 T90 R92
Binding residue
(residue number reindexed from 1)
N21 M23 E24 Q60 K61 V63 V64 T87 R89
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0000049
tRNA binding
GO:0003723
RNA binding
GO:0003735
structural constituent of ribosome
GO:0019843
rRNA binding
Biological Process
GO:0006412
translation
Cellular Component
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Molecular Function
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Cellular Component
External links
PDB
RCSB:7uvz
,
PDBe:7uvz
,
PDBj:7uvz
PDBsum
7uvz
PubMed
37192172
UniProt
B7IA27
|RL5_ACIB5 Large ribosomal subunit protein uL5 (Gene Name=rplE)
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