Structure of PDB 7qh2 Chain F Binding Site BS02

Receptor Information
>7qh2 Chain F (length=467) Species: 33952 (Acetobacterium woodii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNYKKVEASDIAAIKELIPAERVFVGTEIGEDFSHDELGSIHSYPEVLIK
VTSTEEVSKIMKYAYEHNIPVVVRGSGTGLVGACVPLFGGIMLETTLMNN
ILELDTENLTVTVEPGVLLMELSKFVEENDLFYPPDPGEKSATIAGNIST
NAGGMRAVKYGVTRDYVRGLTVVLANGEIIELGGKIVKNSSGYSLKDLVI
GSEGTLCVITKAILKLLPLPKMTLSLLIPFENISDAAGIVPKIIKSKAIP
TAIEFMERQTILFAEDFLGKKFPDSSSNAYILLTFDGNTKEQVEAEYETV
ANLCLAEGAKDVYIVDTVERKDSVWSARGAFLEAIKASTTEMDECDVVVP
RNRIAEFIEFTHDLAKEMDVRIPSFGHAGDGNLHIYVCRDELCQADWEAK
LAEAMDRMYAKALTFEGLVSGEHGIGYAKRKYLLNDFGTEHLALMAGIKQ
TFDPKNLLNPKKVCQMA
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain7qh2 Chain F Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7qh2 Structure-based electron-confurcation mechanism of the Ldh-EtfAB complex.
Resolution2.43 Å
Binding residue
(original residue number in PDB)		H377 H384 E422
Binding residue
(residue number reindexed from 1)		H377 H384 E422
Annotation score1
Enzymatic activity
Enzyme Commision number 1.1.1.436: lactate dehydrogenase (NAD(+),ferredoxin).
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008720 D-lactate dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7qh2, PDBe:7qh2, PDBj:7qh2
PDBsum7qh2
PubMed35748623
UniProtH6LBS1|LCTD_ACEWD Lactate dehydrogenase (NAD(+),ferredoxin) subunit LctD (Gene Name=lctD)

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