Structure of PDB 7k78 Chain F Binding Site BS02

Receptor Information
>7k78 Chain F (length=80) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLKSFLESVIRDSVTY
TEHAKRKTVTSLDVVYALKRQGRTLYGFGG
Ligand information
>7k78 Chain J (length=116) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tatttcttttttaactttcggaaatcaaatacactaatattttaaatttt
attttttaaaaataaactactttttattttttactttttttaaaaatata
ataaaatcaaatatca
Receptor-Ligand Complex Structure
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PDB7k78 Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
P33 R37 R46
Binding residue
(residue number reindexed from 1)
P10 R14 R23
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0006355 regulation of DNA-templated transcription
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
GO:0045943 positive regulation of transcription by RNA polymerase I
Cellular Component
GO:0000500 RNA polymerase I upstream activating factor complex
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0031298 replication fork protection complex
GO:0032991 protein-containing complex

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Cellular Component
External links
PDB RCSB:7k78, PDBe:7k78, PDBj:7k78
PDBsum7k78
PubMed33741944
UniProtP02309|H4_YEAST Histone H4 (Gene Name=HHF1)

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