Structure of PDB 7f0r Chain F Binding Site BS02

Receptor Information
>7f0r Chain F (length=278) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRALDATQLYLNEIGFSPLLTPEEEVHFARLAQKGDPAGRKRMIESNLRL
VVKIARRYVNRGLSLLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIR
QTIERAIMNQTRTIRLPIHVVKELNVYLRAARELTHKLDHEPSPEEIANL
LEKPVAEVKRMLGLNERVTSVDVSLGPDSDKTLLDTLTDDRPTDPCELLQ
DDDLSESIDQWLTELTDKQREVVIRRFGLRGHESSTLEEVGQEIGLTRER
VRQIQVEALKRLREILEKNGLSSDALFQ
Ligand information
>7f0r Chain H (length=40) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cttgacggaaccacacgatgctgtagctcggttgagacga
Receptor-Ligand Complex Structure
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PDB7f0r Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding.
Resolution5.8 Å
Binding residue
(original residue number in PDB)		D140 R146 T149 Y150 W154 Q157 R171 P173 I174 H175
Binding residue
(residue number reindexed from 1)		D84 R90 T93 Y94 W98 Q101 R115 P117 I118 H119
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:0050921 positive regulation of chemotaxis
GO:1900034 regulation of cellular response to heat
GO:1900233 positive regulation of single-species biofilm formation on inanimate substrate
GO:1900377 negative regulation of secondary metabolite biosynthetic process
GO:1900407 regulation of cellular response to oxidative stress
GO:1901000 regulation of response to salt stress
GO:2000142 regulation of DNA-templated transcription initiation
GO:2000145 regulation of cell motility
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f0r, PDBe:7f0r, PDBj:7f0r
PDBsum7f0r
PubMed35859063
UniProtP45684|RPOS_PSEAE RNA polymerase sigma factor RpoS (Gene Name=rpoS)

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