Structure of PDB 7eby Chain F Binding Site BS02

Receptor Information
>7eby Chain F (length=761) Species: 1744839 (Cupriavidus sp. P4-10-C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQID
LWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAE
AFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLN
FTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAAL
KKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLR
YVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYET
DPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADD
ASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQV
YADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYN
PSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSL
RDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGW
DGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAV
LEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFR
HPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMV
LDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVER
AAEKRIELTPR
Ligand information
Ligand IDCO3
InChIInChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
InChIKeyBVKZGUZCCUSVTD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=O)([O-])[O-]
ACDLabs 10.04
CACTVS 3.341		[O-]C([O-])=O
FormulaC O3
NameCARBONATE ION
ChEMBL
DrugBankDB14531
ZINC
PDB chain7eby Chain F Residue 908 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7eby Protein Engineering of d-Succinylase from Cupriavidus sp. for d-Amino Acid Synthesis and the Structural Implications.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		R305 R313 L348 Y433 E460
Binding residue
(residue number reindexed from 1)		R242 R250 L285 Y370 E397
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Biological Process
GO:0017000 antibiotic biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7eby, PDBe:7eby, PDBj:7eby
PDBsum7eby
PubMed
UniProtA0A0N7KZ58

[Back to BioLiP]