Structure of PDB 7dcs Chain F Binding Site BS02

Receptor Information
>7dcs Chain F (length=93) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHN
NMASFVRQLNMYGFRKVVHDTEFQHPCFLRGQEQLLENIKRKV
Ligand information
Receptor-Ligand Complex Structure
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PDB7dcs Structures of heat shock factor trimers bound to DNA.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
K62 R71 N74 R79 K80
Binding residue
(residue number reindexed from 1)
K48 R57 N60 R65 K66
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:7dcs, PDBe:7dcs, PDBj:7dcs
PDBsum7dcs
PubMed34458700
UniProtQ00613|HSF1_HUMAN Heat shock factor protein 1 (Gene Name=HSF1)

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