Structure of PDB 7ckq Chain F Binding Site BS02

Receptor Information
>7ckq Chain F (length=272) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPVRMYLKEIGRVNLLSAKEEIAYAQKIEEGDEESKRRLAEANLRLVVSI
AKRYVGRGMLFLDLIQEGNMGLMKAVEKFDYRKGYKFSTYATWWIRQAIT
RAIADQARTIRIPVHMVETINKLIRVQRQLLQDLGREPTPEEIAEDMDLT
PEKVREILKIAQEPVSLETPIGEEDDSHLGDFIEDQEATSPSDHAAYELL
KEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVGKVFGVTRERIRQI
EAKALRKLRHPSRSKRLKDFLE
Ligand information
Receptor-Ligand Complex Structure
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PDB7ckq The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		W192 R195 Q196 T199 R224 R321 T331 E344 R347
Binding residue
(residue number reindexed from 1)		W93 R96 Q97 T100 R125 R222 T232 E245 R248
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ckq, PDBe:7ckq, PDBj:7ckq
PDBsum7ckq
PubMed33293519
UniProtP06224|SIGA_BACSU RNA polymerase sigma factor SigA (Gene Name=sigA)

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