Structure of PDB 7arj Chain F Binding Site BS02

Receptor Information

>7arj Chain F (length=225) Species: 83333 (Escherichia coli K-12)

ILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSSGSGKSTLLH
LLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDFT
ALENVAMPLLIGKKKPAEINSRALEMLKAVGLDHRANHRPSELSGGERQR
VAIARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVT
HDLQLAKRMSRQLEMRDGRLTAELS

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 7arj Chain F Residue 402

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7arj Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
• Resolution: 3.2 Å
• Binding residue (original residue number in PDB): S49 D170
• Binding residue (residue number reindexed from 1): S46 D167
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 7.6.2.-

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity
• GO:0022857 transmembrane transporter activity
• GO:0140306 lipoprotein releasing activity

Biological Process

• GO:0044873 lipoprotein localization to membrane
• GO:0044874 lipoprotein localization to outer membrane
• GO:0055085 transmembrane transport
• GO:0089705 protein localization to outer membrane

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane
• GO:0043190 ATP-binding cassette (ABC) transporter complex
• GO:0098797 plasma membrane protein complex

External links

• PDB: RCSB:7arj, PDBe:7arj, PDBj:7arj
• PDBsum: 7arj
• PubMed: 33782615
• UniProt: P75957|LOLD_ECOLI Lipoprotein-releasing system ATP-binding protein LolD (Gene Name=lolD)