Structure of PDB 6zs1 Chain F Binding Site BS02

Receptor Information

>6zs1 Chain F (length=154) Species: 759272 (Thermochaetoides thermophila DSM 1495)

MVKAVAVVRGDSKVTGTVTFEQESESSPTIITWDITGHDPNAKRGMHIHT
FGDNTNGCTSAGPHFNPHGKTHGAPTDENRHVGDLGNIETDANGNSKGTM
TDHLVKLIGPESVIGRTVVVHAGTDDLGKGGNEESLKTGNAGPRPACGVI
GIAQ

Ligand information

• Ligand ID: CU
• InChI: InChI=1S/Cu/q+2
• InChIKey: JPVYNHNXODAKFH-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Cu+2]
  CACTVS 3.341: [Cu++]
• Formula: Cu
• Name: COPPER (II) ION
• DrugBank: DB14552
• PDB chain: 6zs1 Chain F Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6zs1 Crystal Structure of a Cu,Zn Superoxide Dismutase From the Thermophilic Fungus Chaetomium thermophilum.
• Resolution: 1.56 Å
• Binding residue (original residue number in PDB): H47 H49 H64 H121
• Binding residue (residue number reindexed from 1): H47 H49 H64 H121
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): H47 H49 H64 H72 H81 D84 H121 R144
• Catalytic site (residue number reindexed from 1): H47 H49 H64 H72 H81 D84 H121 R144
• Enzyme Commision number: 1.15.1.1: superoxide dismutase.

Gene Ontology

Molecular Function

• GO:0004784 superoxide dismutase activity
• GO:0005507 copper ion binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006801 superoxide metabolic process
• GO:0019430 removal of superoxide radicals
• GO:0034599 cellular response to oxidative stress

External links

• PDB: RCSB:6zs1, PDBe:6zs1, PDBj:6zs1
• PDBsum: 6zs1
• PubMed: 33726638
• UniProt: G0S1F8