Structure of PDB 6nqa Chain F Binding Site BS02

Receptor Information
>6nqa Chain F (length=88) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLEN
VIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Ligand information
>6nqa Chain J (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcggatgtatatatctgacacgtgcctggagactagggagtaatcccct
tggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgcta
gagctgtctacgaccaattgagcggcctcggcaccgggattctcga
Receptor-Ligand Complex Structure
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PDB6nqa Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Resolution3.54 Å
Binding residue
(original residue number in PDB)		T30 R36 R45
Binding residue
(residue number reindexed from 1)		T16 R22 R31
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6nqa, PDBe:6nqa, PDBj:6nqa
PDBsum6nqa
PubMed30765112
UniProtP62799|H4_XENLA Histone H4

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