Structure of PDB 6klx Chain F Binding Site BS02

Receptor Information
>6klx Chain F (length=368) Species: 1502 (Clostridium perfringens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDLDTDNDNIPDAYEKNGYTIKDSIAVKWNDSFAEQGYKKYVSSYLESNT
AGDPYTDYQKASGSIDKAIKLEARDPLVAAYPVVGVGMENLIISTNEHAS
SDQGKTVSRATTVQDSNGESWNTGLSINKGESAYINANVRYYNTGTAPMY
KVTPTTNLVLDGETLATIKAQDNQIGNNLSPNETYPKKGLSPLALNTMDQ
FNARLIPINYDQLKKLDSGKQIKLETTQVSGNYGTKNSQGQIITEGNSWS
NYISQIDSVSASIILDTGSQTFERRVAAKEQGNPEDKTPEITIGEAIKKA
FSATKNGELLYFNGIPIDESCVELIFDDNTSEIIKEQLKYLDDKKIYNVK
LERGMNILIKVPSYFTNF
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6klx Chain F Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6klx Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		D219 D221 D223 I225 E230
Binding residue
(residue number reindexed from 1)		D4 D6 D8 I10 E15
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051260 protein homooligomerization
Cellular Component
GO:0005576 extracellular region

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Biological Process
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Cellular Component
External links
PDB RCSB:6klx, PDBe:6klx, PDBj:6klx
PDBsum6klx
PubMed32123390
UniProtQ46221

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