Structure of PDB 6g0y Chain F Binding Site BS02

Receptor Information
>6g0y Chain F (length=171) Species: 11259 (Human respiratory syncytial virus A2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RNPCKFEIRGHCLNGKRCHFSHNYFEWPPHALLVRQNFMLNRILKSMDKS
IDTLSEISGAAELDRTEEYALGVVGVLESYIGSINNITKQSACVAMSKLL
TELNSDDIKKLRDNEELNSPKIRVYNTVISYIESNRKNNKQTIHLLKRLP
ADVLKKTIKNTLDIHKSITIN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6g0y Chain F Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6g0y The Structure of the Human Respiratory Syncytial Virus M2-1 Protein Bound to the Interaction Domain of the Phosphoprotein P Defines the Orientation of the Complex.
Resolution2.42 Å
Binding residue
(original residue number in PDB)		C7 C15 C21 H25
Binding residue
(residue number reindexed from 1)		C4 C12 C18 H22
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0019083 viral transcription
GO:0031564 transcription antitermination
GO:0046782 regulation of viral transcription
GO:0085033 symbiont-mediated activation of host NF-kappaB cascade
Cellular Component
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6g0y, PDBe:6g0y, PDBj:6g0y
PDBsum6g0y
PubMed30425144
UniProtP04545|M21_HRSVA Protein M2-1 (Gene Name=M2-1)

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