Structure of PDB 6c31 Chain F Binding Site BS02

Receptor Information

>6c31 Chain F (length=195) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQF
ADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSG
DPEVRQLILLDAPVVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQP
VRPLAQVLIGALDEAAMFIATADDPKRARRETRQVLRRLIDGMLN

Ligand information

>6c31 Chain J (length=23) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gttaccggcagtctgcttgtaaa

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6c31 Cytokinin Signaling in Mycobacterium tuberculosis.
Resolution	3.0 Å
Binding residue (original residue number in PDB)	R6 T7 Q8 T37 P38 R48 Y52 D57
Binding residue (residue number reindexed from 1)	R1 T2 Q3 T32 P33 R43 Y47 D52
Binding affinity	PDBbind-CN: Kd=357nM

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000976	transcription cis-regulatory region binding
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription

	Cellular Component
GO:0005886	plasma membrane

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External links

PDB	RCSB:6c31, PDBe:6c31, PDBj:6c31
PDBsum	6c31
PubMed	29921668
UniProt	O53623

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