Structure of PDB 5xy3 Chain F Binding Site BS02

Receptor Information
>5xy3 Chain F (length=231) Species: 5722 (Trichomonas vaginalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LQKIAARVEAQKAAYLKKKEELLAAAKANEAKIQERAKKYAAEYVSQTKA
EIDAENKATAEGAFYVPAEAKFAFVIRTKGTNKLHPDVRKILHLFRLNQK
HNAIFVRLNKATIEMLKRVTPQVAFGYPSVDMVRKLIYKLGTANLNGQRI
PIADNQIIKVALGHLCIESVEDLAHEIYTVGPNFAAANRFLAVFKLHAPK
GGYKKINRAYVEGGDYGNREHLIDELIERMI
Ligand information
>5xy3 Chain 3 (length=117) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaagcggccacacccggcuggcaacauccagcuccacuccgaaccuggaa
auuaagcagucgcgggccacaucaguacugggcugggcgacuucccggga
acgugcggugcuugcuu
<<...<<.....<<<<<<<<.....<<<<<<.............>>>>..
>>....>>>>>>.>><<<.<<<.....<<<<<..<<....>>.>>>>>..
..>>>.>>>.>>...>>
Receptor-Ligand Complex Structure
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PDB5xy3 Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Resolution3.2 Å
Binding residue
(original residue number in PDB)		K125 K213 N215 R216 V219 E220
Binding residue
(residue number reindexed from 1)		K117 K205 N207 R208 V211 E212
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

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Biological Process
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Cellular Component
External links
PDB RCSB:5xy3, PDBe:5xy3, PDBj:5xy3
PDBsum5xy3
PubMed28809395
UniProtA2F592

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