Structure of PDB 5x6m Chain F Binding Site BS02

Receptor Information
>5x6m Chain F (length=121) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQP
SKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEF
PFGSKQKEVCINPYHYKRVES
Ligand information
Receptor-Ligand Complex Structure
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PDB5x6m Structural basis for the Smad5 MH1 domain to recognize different DNA sequences.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
R75 K82 H102
Binding residue
(residue number reindexed from 1)
R63 K70 H90
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005667 transcription regulator complex

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Biological Process

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Cellular Component
External links
PDB RCSB:5x6m, PDBe:5x6m, PDBj:5x6m
PDBsum5x6m
PubMed26304548
UniProtP97454|SMAD5_MOUSE Mothers against decapentaplegic homolog 5 (Gene Name=Smad5)

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