Structure of PDB 5vi8 Chain F Binding Site BS02

Receptor Information
>5vi8 Chain F (length=319) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKKAPAKRAAKSAAAKAADSVRAYLKQIGKVALLNAEEEVELAKRIEAGL
YATQKLAELAEKGEKLPVQQRRDMQWICRDGDRAKNHLLEANLRLVVSLA
KRYTGRGMAFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQAITR
AMADQARTIRIPVHMVEVINKLGRIQRELLQDLGREPTPEELAKEMDITP
EKVLEIQQYAREPISLDQTIGDDSQLGDFIEDSEAVVAVDAVSFTLLQDQ
LQSVLETLSEREAGVVRLRFGLTDGQPRTLDEIGQVYGVTRERIRQIESK
TMSKLRHPSRSQVLRDYLD
Ligand information
Receptor-Ligand Complex Structure
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PDB5vi8 Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures.
Resolution2.76 Å
Binding residue
(original residue number in PDB)
E312 R319 R416 T426 L427 R438 E439 R442
Binding residue
(residue number reindexed from 1)
E167 R174 R269 T279 L280 R291 E292 R295
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5vi8, PDBe:5vi8, PDBj:5vi8
PDBsum5vi8
PubMed28703128
UniProtA0QW02

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