Structure of PDB 5vi8 Chain F Binding Site BS02
Receptor Information
>5vi8 Chain F (length=319) Species:
246196
(Mycolicibacterium smegmatis MC2 155) [
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AKKAPAKRAAKSAAAKAADSVRAYLKQIGKVALLNAEEEVELAKRIEAGL
YATQKLAELAEKGEKLPVQQRRDMQWICRDGDRAKNHLLEANLRLVVSLA
KRYTGRGMAFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQAITR
AMADQARTIRIPVHMVEVINKLGRIQRELLQDLGREPTPEELAKEMDITP
EKVLEIQQYAREPISLDQTIGDDSQLGDFIEDSEAVVAVDAVSFTLLQDQ
LQSVLETLSEREAGVVRLRFGLTDGQPRTLDEIGQVYGVTRERIRQIESK
TMSKLRHPSRSQVLRDYLD
Ligand information
>5vi8 Chain P (length=26) [
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agcacaatttaacacttttgtcaagc
Receptor-Ligand Complex Structure
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PDB
5vi8
Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures.
Resolution
2.76 Å
Binding residue
(original residue number in PDB)
E312 R319 R416 T426 L427 R438 E439 R442
Binding residue
(residue number reindexed from 1)
E167 R174 R269 T279 L280 R291 E292 R295
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003700
DNA-binding transcription factor activity
GO:0016987
sigma factor activity
Biological Process
GO:0006352
DNA-templated transcription initiation
GO:0006355
regulation of DNA-templated transcription
GO:0010468
regulation of gene expression
GO:2000142
regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:5vi8
,
PDBe:5vi8
,
PDBj:5vi8
PDBsum
5vi8
PubMed
28703128
UniProt
A0QW02
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