Structure of PDB 5v7q Chain F Binding Site BS02

Receptor Information

>5v7q Chain F (length=170) Species: 1773 (Mycobacterium tuberculosis)

KERYRSEIRDALRKQFGYGNVMQIPTVTKVVVNMGVGEAARDAKLINGAV
NDLALITGQKPEVRRARKSIAQFKLREGMPVGVRVTLRGDRMWEFLDRLT
SIALPRIRDFRGLSPKQFDGVGNYTFGLAEQAVFHEVDVDKIDRVRGMDI
NVVTSAATDDEGRALLRALG

Ligand information

>5v7q Chain B (length=115)

uuacggcggccacagcggcagggaaacgcccggucccauuccgaacccgg
aagcuaagccugccagcgccgaugauacugccccuccggguggaaaagua
ggacaccgccgaaca

.<.<<<<<<.....<<<<<<<<.....<<<<<...............>>>
..>>....>>>>>>.>>.<<........<<<<<....>>>>>........
>>...>>>>>>.>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5v7q Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis.
• Resolution: 3.7 Å
• Binding residue (original residue number in PDB): N31 M33 Q34 Q70 K71 E73 V74 R75 T97 R99 R102
• Binding residue (residue number reindexed from 1): N20 M22 Q23 Q59 K60 E62 V63 R64 T86 R88 R91

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0005886 plasma membrane
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5v7q, PDBe:5v7q, PDBj:5v7q
• PDBsum: 5v7q
• PubMed: 28977617
• UniProt: P9WH83|RL5_MYCTU Large ribosomal subunit protein uL5 (Gene Name=rplE)