Structure of PDB 5gan Chain F Binding Site BS02

Receptor Information
>5gan Chain F (length=415) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PFEILPESIELFRTLALISPDRLSLSETAQILPKIVDLKRILQQQEIDFI
KLLPFFNEIIPLIKSNIKLMHNFLISLYSRRFPELSSLIPSPLQYSKVIS
ILENENYSKNESDELFFHLENKAKLTREQILVLTMSMKTSFKNKEPLDIK
TRTQILEANSILENLWKLQEDIGQYIASKISIIAPNVCFLVGPEIAAQLI
AHAGGVLEFSRIPSCNIASIGKNKHLSHELHTLESGVRQEGYLFASDMIQ
KFPVSVHKQMLRMLCAKVSLAARVDAGQKNGDRNTVLAHKWKAELSKKAR
KLSEAPSISETKALPIPEDQPKKKRAGRKFRKYKEKFRLSHVRQLQNRME
FGKQEQTVLDSYGEEVGLGMSNTSLQQAVGATSGSRRSAGNQAKLTKVMK
HRISEANQQADEFLI
Ligand information
>5gan Chain W (length=80) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guucgcgaacuucguggacauuuggucaauuugaauacagagaucagcag
uuccccugcauaaggaugaaccguuguuuu
<<<<<<<<<.>>>>>>>>>.........<<<..>>>..............
..............................
Receptor-Ligand Complex Structure
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PDB5gan Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		A368 G369 R370 K371 R373
Binding residue
(residue number reindexed from 1)		A326 G327 R328 K329 R331
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
Biological Process
GO:0000244 spliceosomal tri-snRNP complex assembly
GO:0000387 spliceosomal snRNP assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005687 U4 snRNP
GO:0005739 mitochondrion
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071011 precatalytic spliceosome
GO:0097526 spliceosomal tri-snRNP complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5gan, PDBe:5gan, PDBj:5gan
PDBsum5gan
PubMed26829225
UniProtP49704|PRP31_YEAST Pre-mRNA-processing factor 31 (Gene Name=PRP31)

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