Structure of PDB 5brm Chain F Binding Site BS02
Receptor Information
>5brm Chain F (length=160) Species:
9606
(Homo sapiens) [
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DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGT
NIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTI
LKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRREL
APLQELIEKL
Ligand information
>5brm Chain M (length=17) Species:
9606
(Homo sapiens) [
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KRNATSPQVQRPSFMDY
Receptor-Ligand Complex Structure
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PDB
5brm
Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
Resolution
2.651 Å
Binding residue
(original residue number in PDB)
N66 N69 T76 K113 P133 S134 I136
Binding residue
(residue number reindexed from 1)
N15 N18 T25 K62 P82 S83 I85
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5brm
,
PDBe:5brm
,
PDBj:5brm
PDBsum
5brm
PubMed
26108669
UniProt
Q9H8S9
|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)
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