Structure of PDB 3fhz Chain F Binding Site BS02

Receptor Information
>3fhz Chain F (length=155) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANRAGRQARIVAILSSAQVRSQNELAALLAAEGIEVTQATLSRDLEELGA
VKLRGADGGTGIYVVPEDGSPVRGVSGGTDRMARLLGELLVSTDDSGNLA
VLRTPPGAAHYLASAIDRAALPQVVGTIAGDDTILVVAREPTTGAQLAGM
FENLR
Ligand information
Receptor-Ligand Complex Structure
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PDB3fhz The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine.
Resolution3.27 Å
Binding residue
(original residue number in PDB)		R18 T52 A54 T55 R58
Binding residue
(residue number reindexed from 1)		R3 T37 A39 T40 R43
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0034618 arginine binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006525 arginine metabolic process
GO:0006526 L-arginine biosynthetic process
GO:0051259 protein complex oligomerization
GO:1900079 regulation of arginine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3fhz, PDBe:3fhz, PDBj:3fhz
PDBsum3fhz
PubMed19265706
UniProtP9WPY9|ARGR_MYCTU Arginine repressor (Gene Name=argR)

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