Structure of PDB 2xvt Chain F Binding Site BS02

Receptor Information
>2xvt Chain F (length=79) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKNYETAVQFCWNHYKDQMDPIEKDWCDWAMISRPYSTLRDCLEHFAELF
DLGFPNPLAERIIFETHQIHFANCSLVQP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2xvt Chain F Residue 1137 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2xvt Structure of the Extracellular Domain of Human Ramp2
Resolution2.05 Å
Binding residue
(original residue number in PDB)		E101 E105
Binding residue
(residue number reindexed from 1)		E44 E48
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015026 coreceptor activity
Biological Process
GO:0006886 intracellular protein transport
GO:0008277 regulation of G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:2xvt, PDBe:2xvt, PDBj:2xvt
PDBsum2xvt
PubMed
UniProtO60895|RAMP2_HUMAN Receptor activity-modifying protein 2 (Gene Name=RAMP2)

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