Structure of PDB 2ogj Chain F Binding Site BS02

Receptor Information
>2ogj Chain F (length=359) Species: 176299 (Agrobacterium fabrum str. C58) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PILLTNVKPVGFASQSSTDILIGGDGKIAAVGRIDAKAFISPGWVDLHVH
IWHGGTDISIRPSECGAERGVTTLVDAGSAGEANFHGFREYIIEPSRERI
KAFLNLGSIGLVACNRVPELRDIKDIDLDRILECYAENSEHIVGLKVRAS
HVITGSWGVTPVKLGKKIAKILKVPMMVHVGEPPALYDEVLEILGPGDVV
THCFNGKSGSSIMEDEDLFNLAERCEGIRLDIGHGGASFSFKVAEAAIAR
GLLPFSISTDLHGHSMNFPVWDLATTMSKLLSVDMPFENVVEAVTRNPAS
VIRLDMENRLDVADFTVFDLVDADLEATDSNGDVSRLKRLFEPRYAVIGA
EAIAASRYI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2ogj Chain F Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2ogj Crystal structure of a dihydroorotase
Resolution2.62 Å
Binding residue
(original residue number in PDB)		K175 H208 H231
Binding residue
(residue number reindexed from 1)		K146 H179 H202
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.1.-
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0019213 deacetylase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2ogj, PDBe:2ogj, PDBj:2ogj
PDBsum2ogj
PubMed
UniProtQ7CS13|DEACT_AGRFC Deacetylase Atu3266 (Gene Name=Atu3266)

[Back to BioLiP]