Structure of PDB 2ffd Chain F Binding Site BS02

Receptor Information
>2ffd Chain F (length=285) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANK
GAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWI
QYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTST
ADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNG
MQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKAST
PNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2ffd Chain F Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2ffd The structure of fibrinogen fragment D with the 'A' knob peptide GPRVVE.
Resolution2.89 Å
Binding residue
(original residue number in PDB)		D318 D320 F322 E323 G324
Binding residue
(residue number reindexed from 1)		D209 D211 F213 E214 G215
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2ffd, PDBe:2ffd, PDBj:2ffd
PDBsum2ffd
PubMed16689770
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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