Structure of PDB 1zei Chain F Binding Site BS02

Receptor Information
>1zei Chain F (length=53) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTDKAAKGIVEQCCTSICSLYQLEN
YCN
Ligand information
Ligand IDCRS
InChIInChI=1S/C7H8O/c1-6-3-2-4-7(8)5-6/h2-5,8H,1H3
InChIKeyRLSSMJSEOOYNOY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04Oc1cc(ccc1)C
OpenEye OEToolkits 1.5.0Cc1cccc(c1)O
CACTVS 3.341Cc1cccc(O)c1
FormulaC7 H8 O
NameM-CRESOL
ChEMBLCHEMBL298312
DrugBankDB01776
ZINCZINC000000897141
PDB chain1zei Chain F Residue 55 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1zei Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		V12 Y16 C19 G20 G23 F24
Binding residue
(residue number reindexed from 1)		V12 Y16 C19 G20 G23 F24
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1zei, PDBe:1zei, PDBj:1zei
PDBsum1zei
PubMed9708987
UniProtP01315|INS_PIG Insulin (Gene Name=INS)

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