Structure of PDB 1pue Chain F Binding Site BS02

Receptor Information
>1pue Chain F (length=89) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKG
NRKKMTYEKMARALRNYGKTGEVKKVKKKLTYQFSGEVL
Ligand information
Receptor-Ligand Complex Structure
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PDB1pue A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		I172 R173 L174 W215 K219 N221 K223 K229 Y237
Binding residue
(residue number reindexed from 1)		I2 R3 L4 W45 K49 N51 K53 K59 Y67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:1pue, PDBe:1pue, PDBj:1pue
PDBsum1pue
PubMed8602247
UniProtP17433|SPI1_MOUSE Transcription factor PU.1 (Gene Name=Spi1)

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