Structure of PDB 1nzb Chain F Binding Site BS02

Receptor Information
>1nzb Chain F (length=322) Species: 10678 (Punavirus P1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPE
DVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRR
IRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYN
TLLRIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVTK
LVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATH
RLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVN
IVMNYIRNLDSETGAMVRLLED
Ligand information
Receptor-Ligand Complex Structure
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PDB1nzb Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation
Resolution3.1 Å
Binding residue
(original residue number in PDB)
F37 S38 H40 T41 M97 R100 R101 R106 R121 A175 K201 K244 N245 R259 E262 R282 Y283 S287 G288 H289
Binding residue
(residue number reindexed from 1)
F18 S19 H21 T22 M78 R81 R82 R87 R102 A156 K182 K225 N226 R240 E243 R263 Y264 S268 G269 H270
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration

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Molecular Function

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Biological Process
External links
PDB RCSB:1nzb, PDBe:1nzb, PDBj:1nzb
PDBsum1nzb
PubMed12954782
UniProtP06956|RECR_BPP1 Recombinase cre (Gene Name=cre)

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