Structure of PDB 1m1j Chain F Binding Site BS02

Receptor Information

>1m1j Chain F (length=389) Species: 9031 (Gallus gallus)

RENCCILDERFGSYCPTTCGIADFFNKYRLTTDGELLEIEGLLQQATNST
GSIEYLIQHIKTIYPSEKQTLPQSIEQLTQKSKKIIEEIIRYENTILAHE
NTIQQLTDMHIMNSNKITQLKQKIAQLESHCQEPCKDTAEIQETTGRDCQ
DIANKGARKSGLYFIKPQKAKQSFLVYCEIDTYGNGWTVLQRRLDGSEDF
RRNWVQYKEGFGHLSPDDTTEFWLGNEKIHLITTQSTLPYALRIELEDWS
GKKGTADYAVFKVGTEEDKYRLTYAYFIGGEAGDAFDGFNFGDDPSDKSY
TYHNGMRFSTFDNDNDNFEGNCAEQDGSGWWMNRCHAGHLNGPYYIGGVY
SRDTGTNSYDNGIIWATWRDRWYSMKKTTMKIIPFNRLS

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 1m1j Chain F Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1m1j Crystal Structure of Native Chicken Fibrinogen at 2.7 A Resolution
• Resolution: 2.7 Å
• Binding residue (original residue number in PDB): D318 D320 F322 G324
• Binding residue (residue number reindexed from 1): D314 D316 F318 G320
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0005102 signaling receptor binding
• GO:0030674 protein-macromolecule adaptor activity
• GO:0046872 metal ion binding

Biological Process

• GO:0007596 blood coagulation
• GO:0030168 platelet activation
• GO:0051258 protein polymerization

Cellular Component

• GO:0005576 extracellular region
• GO:0005577 fibrinogen complex

External links

• PDB: RCSB:1m1j, PDBe:1m1j, PDBj:1m1j
• PDBsum: 1m1j
• PubMed: 11601975
• UniProt: O93568