Structure of PDB 8ipa Chain EB Binding Site BS02
Receptor Information
>8ipa Chain EB (length=399) Species:
4565
(Triticum aestivum) [
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TARPLVSVKALDGDMATDAAGVPMPHVMKAPIRPDVITFVHRLVSCNSRQ
PYAVSRKAGHQTSAESWGTGRAVSRIPRVGGGGTHRAGQGAFGNMCRGGR
MFAPTRIWRKWHRRVNVRLRRVAVASALAATAVPAIVTARGHRIESVPEF
PLVVSDSAEGIEKTAQAIKVLKQLGAYADAEKAKDSVGIRPGKGKMRNRR
YINRKGPLIVYGTEGSKIVKAFRNLPGVDVANVERLNLLDLAPGGHLGRF
VIWTESAFKKLDEVYGSFEASSSKKKGFVLPRPKMTNADLGRLINSDEVQ
SVVKPINKEVKRREARKNPLKNAAAVLKLNPYFGTARRMAVLAEAARVKA
RKEKINSKRTKLSAEEASKIKAAGKAWYQTMISDSDYTEFDVFSKWLGV
Ligand information
>8ipa Chain SB (length=160) [
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cgacucucggcaacggauaucucggcucucgcaucgaugaagaacguagc
gaaaugcgauaccuggugugaauugcagaaucccgugaaccaucgagucu
uugaacgcaaguugcgcccgaggccauccggccgagggcacgccugccug
ggcgucacgc
.........................................<<<<<<.((
.....>>>....<<<<<<<.....))............>.>>>>.>>..>
>>....<<.....>><<<<..<<<<....>>>>..>>>>...........
..........
Receptor-Ligand Complex Structure
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PDB
8ipa
Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution
3.4 Å
Binding residue
(original residue number in PDB)
P54 A56 S58 K198
Binding residue
(residue number reindexed from 1)
P51 A53 S55 K195
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0003735
structural constituent of ribosome
Biological Process
GO:0006412
translation
Cellular Component
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:8ipa
,
PDBe:8ipa
,
PDBj:8ipa
PDBsum
8ipa
PubMed
38267667
UniProt
A0A3B5ZXX7
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