Structure of PDB 8ipb Chain EA Binding Site BS02

Receptor Information
>8ipb Chain EA (length=164) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLNPMREIKVQKLVLNISVGESGDRLTRAAKVLEQLSGQSPVFSKARYTV
RSFGIRRNEKIACYVTIRGEKAMQLLESGLKVKEYELLRRNFSDTGCFGF
GIQEHIDLGMKYDPSTGIYGMDFFVVLERAGYRVSRRRRCKARVGIHQRV
TKEDAMKWFQVKYE
Ligand information
>8ipb Chain TB (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggaugcgaucauaccagcacuaaggcaucggaucccgucagaacuccgaa
guuaagcgugcuugggcgagaguaguacaaggaugggugaccucuuggga
aguccucguguugcauuccc
<<<<<<<<<....<<<<<<<......<<<<<..............>>>..
>>.....>>>>>.>><<<<<.<.....<.<<<<.<<....>>>>>>.>..
..>.>>>>>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB8ipb Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		N9 M11 R12 Q17 Q45 S46 V48 Y70 V71 T72 R74 G137 R139 V140 R143 R145 R149 G151 I152 H153 Q154
Binding residue
(residue number reindexed from 1)		N3 M5 R6 Q11 Q39 S40 V42 Y64 V65 T66 R68 G131 R133 V134 R137 R139 R143 G145 I146 H147 Q148
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ipb, PDBe:8ipb, PDBj:8ipb
PDBsum8ipb
PubMed38267667
UniProtA0A3B5XX39

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